The International Genetically Engineered Machine (iGEM) Foundation (established in 2003) is a an independent, non-profit organization dedicated to the advancement of Synthetic Biology (Engineering Biotechnologically useful Genetic Constructs). Research, Education via an open community based competition process.
Therefore iGEM’S main program is to spur the iGEM Competition among undergraduate students all over the world. The iGEM competition gives students from about 45 countries registered with iGEM the opportunity to push the boundaries of synthetic biology by tackling everyday issues facing the world. So the real-world problems are cracked by synthetic Biology approaches!
Every year nearly 6000 people dedicate their summer to iGEM projects in their native country laboratories and the short-listed teams come together in the fall to present their research findings in a highly competive annual jamboree event. iGEM 2019 drew 375 shortlisted teams worldwide for a final competition at Boston (Giant Jamboree October 31 to November 4). Out of 57 Gold awardees, IISER-Tirupati was a proud winner of GOLD at its very first attempt!
IISER-Tirupati iGEM team proposed and showed that synthetically generated probacteria can specifically target colon cancer tumour and elicit lactic acid (generated by the tumour) induced imuunomodulator IL-12 that targets the tumour itself. So it was a tumour induced suicide therapy.
Team details and the mentors are mentioned below:
Amartya Pal: BS-MS 2016
Bhabesh Kumar Tripathy: BS-MS 2016
Megha Maria Jacob: BS-MS 2017
Mrugank Dake: BS-MS 2016
Uttara Khatri: BS-MS 2016
Prof Krishna N Ganesh, Director, IISER Tirupati
Prof Basuthkar Jagadeeshwara Rao, Professor & Dean, Biology
Dr. Raju Mukherjee, Assistant Professor, Biology